Watch singer James Darren as he makes two appearances on The Donna Reed Show during the first four seasons.

Watch Bobby Burgess, one of Disney's original Mouseketeers, play a football player in “Mary’s Double Date” on The Donna Reed Show.

When The Donna Reed Show premiered, Campbell's Soup was the sponsor. By the fourth show, everyone was prepared for the show to be canceled.

Richard Deacon is known for playing recurring roles on television shows. Watch him in four episodes of The Donna Reed Show.

Doodles Weaver began his career as a comedian touring with the Spike Jones Music Revue. He made four appearances on The Donna Reed Show.

The Donna Reed Show stretched the envelope in 1962 by inviting Miyoshi Umeki for an episode about an interracial couple.

Singer and songwriter Lesley Gore appears in the last episode of The Donna Reed Show singing her hit song, "It's My Party."

Mark Slade, best known as Blue Cannon in the western series, The High Chaparral (1967), also appeared on The Donna Reed Show (S8, E10).

Cloris Leachman won eight Emmy awards, tying with Julia Louis-Dreyfus. She guests on The Donna Reed Show in Season 4 in Mouse at Play.

Florence MacMichael, known for her roles in My Three Sons, Mister Ed, and The Andy Griffith Show, also appeared on The Donna Reed Show.

Lori Martin, who played Velvet Brown on the NBC version of National Velvet, also appears in All Women are Dangerous on The Donna Reed Show.

Tommy Ivo, an actor and drag racer, appeared in five episodes of The Donna Reed Show as Mary's boyfriend, Herbie Bailey.

Hans Conried was an American actor, comedian, and voice actor. Watch him on The Donna Reed Show in “It’s the Principle of the Thing.”

Child actor Harvey Grant was known for roles in both film and later television. He appears in two early episodes of The Donna Reed Show.

Roberta Shore began her career at age ten, singing country-western songs at supermarket openings with Tex Williams.

John Astin, known for his portrayal of "Gomez Addams" in the hit series The Addams Family, made one appearance on The Donna Reed Show.

Mary Treen appears in the movie It’s a Wonderful Life as Cousin Tilly. She also guests in three episodes of The Donna Reed Show.

Johnny Crawford makes a guest appearance on The Donna Reed Show in “A Very Bright Boy” (Season 4, Episode 15).

Darryl Richard is probably best remembered for the role of Morton "Smitty" Smith, Jeff Stone's best friend on The Donna Reed Show.

Carl Betz, best known for playing Donna Reed's husband in The Donna Reed Show, later went on to play an attorney in Judd For the Defense.