Janet Landgard was a regular on The Donna Reed Show, appearing in the role of Karen, Jeff’s girlfriend during Seasons 6, 7 and 8.

Patricia Barry, an Iowa native, appears on The Donna Reed Show in "All is Forgiven" (Season 4, Episode 8).

Jimmy Hawkins appears with Donna Reed in It's a Wonderful LIfe as Tommy Bailey. He later appeared numerous times on The Donna Reed Show.

William Lanteau, known for his role as mayor Chester Wanamaker in the sitcom Newhart, made five appearances on The Donna Reed Show.

Watch Ben Gage, a radio singer and announcer who also dubbed the voice of non-singing actors, as he appears on The Donna Reed Show.

Watch Kathryn Givney, an American character actress on stage and in films, appear on The Donna Reed Show in Season 5, Episode 24.

Whit Bissel appears with Donna Reed in the film, Three Hours to Kill (1954) and again, as a guest star, on The Donna Reed Show.

Hayden Rorke, best known for his role in I Dream of Jeannie, made one appearance on The Donna Reed Show.

Margaret Dumont, best remembered as the comic foil to the Marx Brothers, made an appearance on The Donna Reed Show (S 1, E 34).

Alice Pearce, the nosy neighbor Gladys Kravitz in "Bewitched," also made an appearance on The Donna Reed Show.

Director Jeffrey Hayden discusses working with Donna Reed on The Donna Reed Show in a Television Academy Foundation interview.

Buster Keaton, the famous silent screen star, had Donna Reed in stitches as he did a three-minute, unscripted routine on The Donna Reed Show

William WindomWindom appears in two episodes of The Donna Reed Show: “All is Forgiven” (S4, E 8) and “Wide Open Spaces” (S4, E25).

The Donna Reed Show originally aired on ABC on September 24, 1958 and ran for 275 episodes before it was eventually canceled in 1966.

Stu Phillips, the composer of the theme tune to the television series Battlestar Galactica, also produced hit songs for The Donna Reed Show.

Swoosie Kurtz was born in Omaha, Nebraska and got her entry into television in 1962 with a small part on The Donna Reed Show.

Carole Wells started her career at age 12 in a commercial for Dial soap. She appears in two episodes of The Donna Reed Show.

Jim Davis, best known for his role as Jock Ewing in the CBS soap, Dallas, guest-stars on The Donna Reed Show in "Pioneer Woman" (S5, E23).

Candy Moore appeared nine times on The Donna Reed Show, five of which as Angie Quinn, the girlfriend of series character Jeff Stone.

Cecil Kellaway guest-stars on The Donna Reed Show in “The Fabulous O’Hara” (Season 4, Episode 13). He appears as a compulsive horse player.